3-(1-Boc-4-piperidyloxy)benzoic acid

3-(1-Boc-4-piperidyloxy)benzoic acid - Names and Identifiers

Name	1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester
Synonyms	3-(1-Boc-4-piperidyloxy)benzoic acid 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE 3-({1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)benzoic acid 1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-di... 4-(3-Carboxy-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester 1-Piperidinecarboxylic acid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester
CAS	250681-69-7

3-(1-Boc-4-piperidyloxy)benzoic acid - Physico-chemical Properties

Molecular Formula	C17H23NO5
Molar Mass	321.37
Storage Condition	Room Temprature

3-(1-Boc-4-piperidyloxy)benzoic acid - Introduction

1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimenthylethyl) ester, also known as 1-Piperidinecarboxylic acid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimenthylethyl) ester, it is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline powder
-molecular formula: C18H23NO5
-Molecular weight: 337.38g/mol
-Melting point: About 128-131 ° C
-Solubility: Soluble in common organic solvents, such as methanol, ethanol, dimethylformamide

Use:
1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester is commonly used in organic synthesis and can be used as an intermediate of piperidine compounds. It can be used to synthesize biologically active compounds, such as drugs, pesticides and other organic compounds.

Method:
Its preparation is usually carried out by the following steps:
1. Through the SN2 reaction, 1-chloro-4-piperidinol reacts with P-Hydroxybenzoic acid to generate 4-(3-carboxyphenoxy)-1-piperidinol;
2. By protecting this carboxyl compound, 1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester is obtained.

Safety Information:
1-Piperidinecarboxylicacid, 4-(3-carboxyphenoxy)-, 1-(1,1-dimethylethyl) ester shall be used and stored in accordance with general laboratory safety practices. It is an organic compound that may be irritating to the eyes, skin and respiratory system. Appropriate protective equipment such as laboratory gloves and eye protection should be worn during operation. Avoid contact with oxidizing agents during handling and storage.

Last Update：2024-04-09 02:00:44